Mitochondrial Genetic Disorders: Challenges & Opportunities

New Hopes and Challenges for Treatment of Neurodegenerative Disorders: Great Opportunities for Young Neuroscientists

Mitochondrial Genetic Variation in Iranian Infertile Men with Varicocele

Objective Several recent studies have shown that mitochondrial DNA mutations lead to major disabilities and premature death in carriers. More than 150 mutations in human mitochondrial DNA (mtDNA) genes have been associated with a wide spectrum of disorders. Varicocele, one of the causes of infertility in men wherein abnormal inflexion and distension of veins of the pampiniform plexus is observe...

Mitochondrial DNA Mutations, Pathogenicity and Inheritance

Mitochondria contain their own DNA (mtDNA), which codes for 13 proteins (all subunits of the respiratory chain complexes), 22 tRNAs and 2 rRNAs. Several mtDNA point mutations as well as deletions have been shown to be causative in well-defined mitochondrial disorders. A mixture of mutated and wild type mtDNA (heteroplasmy) is found in most of these disorders. Inheritance of mtDNA is maternal, a...

Situating Multimodal Learning Analytics

The digital age has introduced a host of new challenges and opportunities for the learning sciences community. These challenges and opportunities are particularly abundant in multimodal learning analytics (MMLA), a research methodology that aims to extend work from Educational Data Mining (EDM) and Learning Analytics (LA) to multimodal learning environments by treating multimodal data. Recogniz...

Inm-6: Molecular Genetic Basis of Infertility

Background: Sexual reproduction affords the stands for conserving genetic characteristics and sequentially, genetic inconsistency may influence the capability to imitate. Materials and Methods: Research was conducted by subject in PubMed and other databases. Results: A significant number of genotypes have been related with infertility phenotypes and evaluation of precise genes in humans and mod...